There is no river on earth where so many dreams were dreamt, where so many dreams came true or fell apart, where the dividing line between life and death is as thin as on the Mississippi - North America's great river. The Mississippi is the world's third largest river. From the Canadian border to New Orleans, from Helena in the Rocky Mountains to Pittsburgh, it drains 31 US states and two Canadian provinces. Since the first human beings set foot on the North-American subcontinent, the face of the river has changed dramatically. This epic film shows the great American river in cinematically beautiful images and emotions. Moving cameras show the endlessness of the land, the impenetrable wilderness and, in stark contrast, the shining steel facades of modern metropolises. The film also reveals a fascinating world inhabited by rare plant and animal wildlife with a distinctly exotic touch. At the same time, it invites us on a journey through history. In several episodes, with the aid of CGI we travel into the past from characteristic sites.